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Double set up technique as a bailout of diagonal branch coronary perforation: a case report

2024-09-23T02:55:37Z

Title: Double set up technique as a bailout of diagonal branch coronary perforation: a case report Authors: Syukri, Muhammad; Yanni, Mefri; Syafri, Masrul; Phalguna, Shindu; Firmansyah, Alles; Sari Mutma Indah, Merlin; Mahendra, Ivan; Zulkarnain, Hadi Abstract: Double set up technique as a bailout of diagonal branch coronary perforation: a case report Muhammad Syukri1 , Mefri Yanni1 , Masrul Syafri1 , Shindu Phalguna2 , Alles Firmansyah2 , Merlin Sari Mutma Indah2 , Ivan Mahendra3 , Hadi Zulkarnain4 Case Report/Series ABSTRACT Coronary artery perforation is a rare but potentially life-threatening complication of percutaneous coronary intervention (PCI). A 55-year-old male with a history of implanted stent on the left main ostium to the proximal left circumflex artery (LCX) and distal right coronary artery, and chronic total occlusion (CTO) on ostium left anterior descending (LAD). PCI was performed using a stiff wire to cross the CTO body in LAD. We performed an injection and confirmed the presence of extravasation. We successfully managed to stop the bleeding by placing the tips of floppy wire that were cut into pieces. A drainage pathway was made through thoracotomy for pericardial effusion. Angiography showed persisting extravasation at the wire insertion site. We then made our own covered stent. We implanted on the osteal LAD until proximal LCX. Repeated angiography showed no contrast extravasated from the perforation site, and the patient was stabilized and discharged. KEYWORDS complication, coronary artery, stent

Psychosocial impacts of coughing in public places during the COVID-19 pandemic: a cross-sectional study in the western region of Saudi Arabia

2024-09-23T02:51:09Z

Title: Psychosocial impacts of coughing in public places during the COVID-19 pandemic: a cross-sectional study in the western region of Saudi Arabia Authors: Dakheel Alahmadi, Abdulrahman; Yunus Mandil, Amjad; Mohammed Alshamran, Abdulaziz; Hani Alharbi, Mohsen; Eldigire Ahmed, Mohamed; Suresh Kumar, Raju Abstract: Psychosocial impacts of coughing in public places during the COVID-19 pandemic: a cross-sectional study in the western region of Saudi Arabia Abdulrahman Dakheel Alahmadi1,2, Amjad Yunus Mandili1,2, Abdulaziz Mohammed Alshamrani1,2, Mohsen Hani Alharbi1,2, Mohamed Eldigire Ahmed2,3, Raju Suresh Kumar2,3 Community Research ABSTRACT BACKGROUND Dry cough is a prevalent symptom of COVID-19. During the pandemic, people may mistake this cough for symptoms associated with other respiratory diseases. This increases the risk of individuals with a cough being falsely judged as having COVID-19. This study aimed to investigate the impact of coughing in public places on adults’ mental and social well-being during the COVID-19 pandemic and to explore the role of demographic factors in the relationship between coughing and psychosocial life in public places in the western region of Saudi Arabia. METHODS This cross-sectional study was conducted in the western region of Saudi Arabia, targeting healthy adults aged ≥18 years. The participants were randomly selected using a cluster sampling technique. Data were collected through a self-administered validated questionnaire to explore the psychosocial impact of coughing in public places during the COVID-19 pandemic. Additionally, the questionnaire collected demographic information, smoking habits, cough frequency, consumption of cough medications, history of mild respiratory diseases, and family history of chronic respiratory illnesses. The mean and standard deviation were used to calculate continuous variables, and frequency and percentages were used to present categorical variables. We analyzed the relationships between study variables using the analysis of variance test. RESULTS 288 adults participated in the study, with a 67.2% agreement score. 82.0% of the participants avoided people who coughed in public, while 51.8% felt angry and frustrated when someone coughed in public during the pandemic. CONCLUSIONS COVID-19 has changed how people react to coughing in public. Mild coughs can be mistaken for COVID-19, leading to avoidance. KEYWORDS cough, COVID-19, psychosocial factors, public, stress

Predictor of recurrent exacerbations in pediatric asthma

2024-09-23T02:44:07Z

Title: Predictor of recurrent exacerbations in pediatric asthma Authors: Cong Tran, Ly; Viet Phan, Hung; Vo-Pham-Minh, Thu Abstract: Predictor of recurrent exacerbations in pediatric asthma Ly Cong Tran1 , Hung Viet Phan1 , Thu Vo-Pham-Minh2 , Nghia Quang Bui1 , Chuong Nguyen-Dinh-Nguyen1 , Nguyen Thi Nguyen Thao1 , Ai Uyen Nguyen Huynh1 , Nhu Thi Huynh Tran1 , Phuong Minh Nguyen1 Medical Journal of Indonesia Clinical Research ABSTRACT BACKGROUND Asthma imposes a heavy morbidity burden during childhood. Severe persistent asthma significantly increases patients’ risk of exacerbations, hospital admissions, and mortality and often substantially impairs their quality of life. This study aimed to identify high-risk patients for exacerbation recurrence using spirometric parameters. METHODS A prospective cohort study involving patients with asthma aged 6–15 years was conducted at the principal children’s hospital in Mekong Delta, Vietnam, from June 2020 to June 2022. Demographic, clinical, and lung function characteristics of the patients were collected. Spirometry measurement parameters were utilized as predictive factors for the short-term asthma exacerbation recurrence. RESULTS Among all patients (mean age of 9.5 years old), 10.4% experienced recurrent exacerbations. FEV1 , FVC, FEV1 /FVC, FEF25–75, FEF25–75/FVC, and PEF, gradually decreased with increasing exacerbation severity (p<0.01). All patients showed a positive bronchodilator responsiveness (BDR), with a mean value of 16.85 (3.00)%, which was significantly different between the severe and non-severe asthma groups (20.53 [2.83] versus 16.00 [2.35], p<0.001). After adjusting in multivariable logistic regression, a BDR ≥20% was identified as the sole independent factor associated with an increased risk of asthma exacerbation recurrence (aOR 6.95, 95% CI 1.08–44.75, p = 0.041). CONCLUSIONS A high BDR can serve as a predictor of acute asthma exacerbation recurrence. KEYWORDS asthma, children, exacerbation, prognosis, spirometry

Efficacy of cilostazol in promoting the maturation of newly created arteriovenous fistula in patients with end-stage renal disease: a systematic review and meta analysis

2024-09-23T02:38:47Z

Title: Efficacy of cilostazol in promoting the maturation of newly created arteriovenous fistula in patients with end-stage renal disease: a systematic review and meta analysis Authors: Alvenus Willim, Herick; Sugandi, Erica; Rosa, Rosa; Ariyanto San, Alvin; Khouw, Hengky Abstract: Efficacy of cilostazol in promoting the maturation of newly created arteriovenous fistula in patients with end-stage renal disease: a systematic review and meta analysis Herick Alvenus Willim,1 Erica Sugandi,2 Rosa,3 Alvin Ariyanto Sani,4 Hengky Khouw4 Clinical Research ABSTRACT BACKGROUND Arteriovenous fistula (AVF) is considered the gold standard for vascular access in hemodialysis. However, achieving the successful maturation of AVF remains a challenge. Cilostazol, a phosphodiesterase-3 inhibitor, has shown promise in enhancing AVF maturation. This study aimed to assess the clinical efficacy of cilostazol in promoting AVF maturation. METHODS This meta-analysis was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A comprehensive systematic literature search was performed using PubMed, ScienceDirect, Cochrane Library, ProQuest, and Google Scholar to identify studies investigating the efficacy of cilostazol on the maturation of newly created AVF in patients with end-stage renal disease and published up to August 2023. The intervention group received perioperative cilostazol therapy, while the control group did not receive cilostazol. The outcomes were the maturation rate of AVF and AVF-related complications. Meta-analysis was conducted using Review Manager software version 5.3. RESULTS 5 studies involving 549 patients were included. The intervention group comprised 228 patients, while the control group comprised 321 patients. In the pooled analysis, patients in the intervention group had a significantly higher rate of AVF maturation (odds ratio [OR] = 2.18, 95% confidence interval [CI]: 1.29–3.68, p = 0.003, I2 = 47%) and a lower rate of AVF-related complications (OR = 0.46, 95% CI: 0.28–0.77, p = 0.003, I2 = 27%) compared to the control. CONCLUSIONS Cilostazol was associated with a higher rate of AVF maturation and a lower rate of AVF-related complications. KEYWORDS arteriovenous fistula, cilostazol, end-stage renal disease, hemodialysis