http://localhost:8080/xmlui/handle/123456789/5140 2026-04-12T03:15:50Z 2026-04-12T03:15:50Z Domi, Jacintha Grootswagers, Pol vanLoon, Luc JC Groot1, Lisette CPGM de http://localhost:8080/xmlui/handle/123456789/5144 2023-06-23T08:12:26Z 2022-01-01T00:00:00Z

Title: Perspective:VeganDietsforOlderAdults? APerspectiveOnthePotentialImpactOnMuscle MassandStrength Authors: Domi, Jacintha; Grootswagers, Pol; vanLoon, Luc JC; Groot1, Lisette CPGM de Abstract: Consumers are increasingly encouraged to consume more plant-based foods and lower their consumption of foods from animal origin. Concurrently, older adults are recommended to consume an adequate amount of high-quality dietary protein for the prevention of age-related muscle loss. In the current Perspective article, we discuss why it may not be preferredto consume a vegan diet at an older age. Our perspective is based on the proposed lower bioavailability and functionality of proteins in a vegan diet due to the matrix of the whole-food protein sources,the lower essential amino acid (EAA) content, and specific EAA deficiencies in proteins derived from plant-based foods. We propose that a vegan diet increasestheriskofaninadequateproteinintakeatanolderageandthatcurrentstrategiestoimprovetheanabolicpropertiesofplant-basedfoods arenotfeasibleformanyolderadults.Weproviderecommendationsforfurtherresearchtosubstantiatetheremainingknowledgegapsregarding theconsequencesofavegandietonskeletalmusclemassandstrengthatanolderage

2022-01-01T00:00:00Z Parr, Evelyn B Devlin, Brooke L Hawley1, John A http://localhost:8080/xmlui/handle/123456789/5143 2023-06-23T07:51:56Z 2022-01-01T00:00:00Z

Title: Perspective:Time-RestrictedEating—Integrating theWhatwiththeWhen Authors: Parr, Evelyn B; Devlin, Brooke L; Hawley1, John A Abstract: Time-restrictedeating(TRE)isapopulardietarystrategythatemphasizesthetimingofmealsinalignmentwithdiurnalcircadianrhythms,permitting adlibitumenergyintakeduringarestricted(∼8–10h)eatingwindoweachday.Unlikeenergy-restricteddietsorintermittentfastinginterventions thatfocusonweightloss,manyofthehealth-relatedbenefitsofTREareindependentofreductionsinbodyweight.However,TREresearchtodate has largely ignored what food is consumed (i.e., macronutrient composition and energy density), overlooking a plethora of past epidemiological andinterventionaldietaryresearch.TodeterminesomeofthepotentialmechanismsunderpinningthebenefitsofTREonmetabolichealth,future studiesneedtoincreasetherigorofdietarydatacollected,assessed,andreportedtoensureaconsistentandstandardizedapproachinTREresearch. ThisPerspectivearticleprovidesanoverviewofstudiesinvestigatingTREinterventionsinhumansandconsidersdietaryintake(bothwhatandwhen foodiseaten)andtheirimpactonselectedhealthoutcomes(i.e.,weightloss,glycemiccontrol).Integratingexistingdietaryknowledgeaboutwhat foodis eaten withour recent understanding onwhen foodshouldbe consumedisessential to optimizethe impact of dietarystrategies aimed at improvingmetabolichealthoutcomes.

2022-01-01T00:00:00Z Jandaghi, Parisa Hosseini, Zeinab http://localhost:8080/xmlui/handle/123456789/5142 2023-06-23T07:47:34Z 2022-01-01T00:00:00Z

Title: TheRoleofImmunomodulatoryNutrientsin AlleviatingComplicationsRelatedtoSARS-CoV-2: AScopingReview Authors: Jandaghi, Parisa; Hosseini, Zeinab Abstract: The recent coronavirus disease 2019 (COVID-19) pandemic has warranted the need to investigate potential therapies or prophylaxis against this infectiousrespiratorydisease.ThereisemergingevidenceaboutthepotentialroleofnutrientsonCOVID-19inadditiontousingmedicationssuchas hydroxychloroquineandazithromycin.Thisscopingreviewaimstoexploretheliteratureevaluatingtheeffectofimmunomodulatorynutrientson theoutcomesincludinghospitalization,intensivecareunitadmission,oxygenrequirement,andmortalityinCOVID-19patients.Aliteraturesearch of databases including Medline, EMBASE, CINAHL, Web of Science, Cochrane, Scopus, and PubMed, as well as hand-searching in Google Scholar (upto10February2021)wasconducted.Allhumanstudieswithdifferentstudydesignsandwithoutlimitationonpublicationyearwereincluded except for non-English-language and review articles. Overall, out of 4412 studies, 19 met our inclusion criteria. Four studies examined the impact of supplementation with vitamin C, 4 studies – zinc, 8 studies – vitamin D, and 3 studies investigated the combination of 2 (zinc and vitamin C) or3(vitaminD,vitaminB-12,andmagnesium)nutrients.Althoughlimiteddataexist,availableevidencedemonstratedthatsupplementationwith immune-supportivemicronutrientssuchasvitaminsDandCandzincmaymodulateimmunityandalleviatetheseverityandriskofinfection.The effectiveness of vitamin C, vitamin D, and zinc on COVID-19 was different based on baseline nutrient status, the duration and dosage of nutrient therapy, time of administration, and severity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease. This review indicated thatsupplementationwithhigh-dosevitaminC,vitaminD,andzincmayalleviatethecomplicationscausedbyCOVID-19,includinginflammatory markers,oxygentherapy,lengthofhospitalization,andmortality;however,studiesweremixedregardingtheseeffects.Furtherrandomizedclinical trialsarenecessarytoidentifythemosteffectivenutrientsandthesafedosagetocombatSARS-CoV-2

2022-01-01T00:00:00Z Mignogna, Cristiana Costanzo, Simona Ghulam, Anwal http://localhost:8080/xmlui/handle/123456789/5141 2023-06-23T07:41:55Z 2022-01-01T00:00:00Z

Title: ImpactofNationwideLockdownsResultingfrom theFirstWaveoftheCOVID-19PandemiconFood Intake,EatingBehaviors,andDietQuality: ASystematicReview Authors: Mignogna, Cristiana; Costanzo, Simona; Ghulam, Anwal Abstract: The lockdowns resulting from the first wave of the coronavirus disease 2019 (COVID-19) pandemic impacted deeply on all life activities, including diet. We performed a systematic review to investigate changes in food intake, eating behaviors, and diet quality during lockdown as compared withbeforethelockdown.Aliteraturesearchwasperformedusing3electronicdatabasesfrominceptionuntil13June2021.Observationalstudies evaluating changes in general populations during the COVID-19 pandemic lockdown were eligible. Of 1963 studies retrieved from the search strategy,95metinclusioncriteria(85inadults,10inchildren/adolescents),andthemajoritywereofhighquality(72.6%).Mostofthestudieswere web-basedsurveysusingconveniencesampling,mainlyfocusedonvariationsintheconsumptionoffoodsandeatingbehaviorsduringlockdown, whereas only 15 studies analyzed diet quality through dietary indices. On the basis of the definition of a healthful diet as reflected by a traditional Mediterranean diet, an increase in recommended foods such as fruit and vegetables, legumes, cereals, and olive oil was observed, although a sharp decrease in fish intake and an increase in dairy products were documented. Accordingly, a reduction in foods that should be eaten less frequentlywasreported—namely,redandprocessedmeat.However,ahigherconsumptionofunhealthyfoods(e.g.,snacksandsweets)wasalso observed.ResultsindicatedimproveddietqualityinEurope,especiallyamongMediterraneancountries,withtheexceptionofFrance,whileaswitch to poor nutrient patterns was observed in Colombia and Saudi Arabia. Analyses of eating behaviors suggest an increase in food intake, number of daily meals, and snacking. In conclusion, changes in intake of major food groups, apart from fish intake, were in line with the definition of a traditional Mediterranean diet, indicating a consistent moderate improvement in dietary habits worldwide. This review protocol was registered at https://www.crd.york.ac.uk/prospero/asCRD42020225292

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