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A Case Study of Psoriasis Vulgaris After COVID-19 Vaccination in Saudi Arabia

2025-07-22T02:25:30Z

Title: A Case Study of Psoriasis Vulgaris After COVID-19 Vaccination in Saudi Arabia Authors: Alwafi, Hassan; Alsulaimani, Nedaa; Almalki, Mohammed E.; Mohammad Banjar, Asma; Abdullah Alamri, Reham; Alwafi, Danya Abstract: Abstract Since the COVID-19 vaccines have been approved, worldwide reports of adverse events have been reported. Although a few cases of Psoriasis vulgaris have been reported after COVID-10 vaccination, there is currently limited evidence to establish a direct relationship between the vaccine and this condition. A 27-year-old Saudi woman, previously healthy and had no medical issues, reported skin lesions on her lower legs, which she noticed ten (10) days after receiving the first dose of the Pfizer COVID-19 vaccine. The patient had no prior history of such lesions or any family history of psoriasis. Joint pain was not observed. A diagnosis of psoriasis vulgaris was made, and the patient was treated with Daivobet® cream, urea cream 10%, and full-body NB-UVB light therapy three times a week for up to two months. The patient's condition improved partially. This report presents the first known case of psoriasis vulgaris after the COVID-19 vaccine in the Middle East. Further research is needed to fully understand this connection. The study emphasizes the significance of a thorough medical history and evaluation for precise diagnosis and treatment. Keywords: COVID-19, drug-related side effects and adverse reactions, SARS-CoV-2, vaccines, vulgaris

Success Rate and Complications of Percutaneous Nephrolithotomy (PCNL) in Nephrolithiasis Patients

2025-07-22T02:22:14Z

Title: Success Rate and Complications of Percutaneous Nephrolithotomy (PCNL) in Nephrolithiasis Patients Authors: Kevin Stein, Lambok; Safriadi, Ferry Abstract: Abstract Percutaneous Nephrolithotomy (PCNL) is the standard management method for kidney stones due to its high success rates. This process is associated with risks, including complications such as infection and bleeding. This study aimed to evaluate the complications and success rates of PCNL in nephrolithiasis patients and provide important insights for clinical decision-making. Data were collected from patients undergoing PCNL for nephrolithiasis at Dr. Hasan Sadikin General Hospital Bandung, Indonesia, in the form of demographic data, stone parameters, and postoperative complications. Data were then analyzed statistically to identify the associated factors. This study was conducted at the Urology Department of the hospital from January to December 2023, involving 80 nephrolithiasis cases. Predominantly, 67.5% of patients were males, with 63.7% in the age group of above 50 years. Multiple stones were the most common (55%), with stone sizes of ≥1.5 cm prevalent in 95% of cases. Left-sided stones (43.8%) were most frequent, followed by rightsided (36.2%) and bilateral stones (20%). Hydronephrosis complications were present in 36.2% of cases, with 100% stone clearance found in Guy Stone Score (GSS) grade 1 cases, while GSS grade 4 cases exhibited the lowest stone clearance rate at 45.4%. This study provided insights into nephrolithiasis demographics, stone characteristics, and postoperative outcomes. Male predominance, multiple stones, high rates of stone clearance, and postoperative complications, particularly in the Guy’s score system, underscore the need for proper management strategies and further research in this field. Keywords: Complication, nephrolithiasis, percutaneous nephrolithotomy, success rate

Comparison of CONUT Score, SGA Score, and GLIM Score as Gold Standard for Colorectal Cancer Patients

2025-07-22T02:20:45Z

Title: Comparison of CONUT Score, SGA Score, and GLIM Score as Gold Standard for Colorectal Cancer Patients Authors: Marcella, Marcella; Rudiman, Reno; Yohana, Raden Abstract: Abstract Malnutrition in colorectal cancer increases toxicity, worsens quality of life, and reduces body functions. Early identification of malnutrition is crucial to determine treatments. This study compared the Global Leadership Initiative on Malnutrition (GLIM) score as the standard nutritional status screening tool to the Controlling Nutritional Status (CONUT) and Subjective Global Assessment (SGA) scores. This study expected to identify a new nutritional status screening tool for colorectal cancer patients. This was a cross-sectional diagnostic study on 60 colorectal cancer patients treated at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia from August 16, 2022 to July 16, 2023. Results revealed that the CONUT score had a sensitivity, specificity, accuracy, and effectiveness values of 80.4%, 0.0%, 85%, and 85%, respectively, in detecting malnutrition. The SGA score had a sensitivity value of 100%, a specificity value of 21.95%, an accuracy value of 85%, and an effectiveness of 85% in detecting malnutrition. When compared with the GLIM score as the gold standard, which is assumed to have a sensitivity and specificity values of 100%, the SGA score was better than the CONUT score for detecting malnutrition in colorectal cancer patients. The SGA score is closest to the GLIM score as the gold standard for assessing malnutrition in colorectal cancer patients.. Keywords: Colorectal cancer, controlling nutritional status, global leadership initiative on malnutrition, malnutrition, subjective global assessment

Neutrophil Lymphocyte Ratio and Mortality in Patients with Acute Limb Ischemia

2025-07-22T02:18:58Z

Title: Neutrophil Lymphocyte Ratio and Mortality in Patients with Acute Limb Ischemia Authors: Hapsari, Putie; Marfen, Teguh; Bayu Nugroho, Hendri Abstract: Abstract Acute Limb Ischemia (ALI) is a sudden decrease in limb perfusion with a potential of limb loss and is an indication for immediate vascular intervention. Apart from reducing the quality of life, the mortality rate in ALI is reported to be high, i.e., around 40%. Neutrophil Lymphocyte Ratio (NLR) can be used to reflect the inflammatory process in this condition. This study aimed to assess the correlation of NLR to mortality rate in ALI Rutherford Category III patients treated in Dr. Hasan Sadikin General Hospital Bandung, Indonesia. This was a cross-sectional analytical observative retrospective study on data collected from medical records of ALI Rutherford Category III patients treated in the hospital from 2019 to 2022. Sampling was performed consecutively and data were processed using the SPSS with univariate analysis and bivariate analysis using Kendall's tau b analysis test. Results demonstrated that of a total of 46 patients, the majority were female patients (n=31) and 28 patients died. The mean NLR levels in patients who survived was 5.8, in contrast with 9.7 observed among those who died. The statistical test results showed a significant correlation between the NLR and mortality rate of ALI Rutherford category III patients (p<0.05), albeit weak positive correlation (r value=0.35). The higher the NLR value was, the higher the risk of death. Hence, the NLR value could be used to recognize the risk of death among these patients. Keywords: Acute limb ischemia (ALI), NLR, mortality rate